2017 INIAstress Publications

Anthenelli RM, Heffner JL, Wong E, Tibbs J, Russell K, Isgro M, Dinh E, Wehrle C, Worley MJ, Doran N. A Randomized Trial Evaluating Whether Topiramate Aids Smoking Cessation and Prevents Alcohol Relapse in Recovering Alcohol-Dependent Men. Alcohol Clin Exp Res. 2017 Jan;41(1):197-206. doi: 10.1111/acer.13279. Epub 2016 Dec 28. PubMed PMID: 28029173; PubMed Central PMCID: PMC5310526.

Beattie MC, Maldonado-Devincci AM, Porcu P, O'Buckley TK, Daunais JB, Grant KA, Morrow AL. Voluntary ethanol consumption reduces GABAergic neuroactive steroid (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) in the amygdala of the cynomolgus monkey. Addict Biol. 2017 Mar;22(2):318330. doi: 10.1111/adb.12326. Epub 2015 Dec 2. PubMed PMID: 26625954; PubMed Central PMCID: PMC4896863.

Bogenpohl JW, Mignogna KM, Smith ML, Miles MF. Integrative Analysis ofGenetic, Genomic, and Phenotypic Data for Ethanol Behaviors: A Network-Based Pipeline for Identifying Mechanisms and Potential Drug Targets. Methods Mol Biol. 2017;1488:531-549. PubMed PMID: 27933543; PubMed Central PMCID: PMC5152688.

Cannady R, McGonigal JT, Newsom RJ, Woodward JJ, Mulholland PJ, Gass JT. Prefrontal cortex K(Ca)2 channels regulate mGlu(5)-dependent plasticity and extinction of alcohol-seeking behavior. J Neurosci. 2017 Mar 20. pii: 2873-16. doi: 10.1523/JNEUROSCI.2873-16.2017. [Epub ahead of print] PubMed PMID: 28320841.

Fordahl SC, Jones SR. High-Fat-Diet-Induced Deficits in Dopamine Terminal Function Are Reversed by Restoring Insulin Signaling. ACS Chem Neurosci. 2017 Feb 15;8(2):290-299. doi: 10.1021/acschemneuro.6b00308. PubMed PMID: 27966885.

Gioia DA, McCool B. Strain-Dependent Effects of Acute Alcohol on Synaptic Vesicle Recycling and Post-Tetanic Potentiation in Medial Glutamate Inputs to the Mouse Basolateral Amygdala. Alcohol Clin Exp Res. 2017 Apr;41(4):735-746. doi:10.1111/acer.13343. Epub 2017 Feb 18. PubMed PMID: 28118494; PubMed Central PMCID: PMC5378618.

Hasirci AS, Maldonado-Devincci AM, Beattie MC, O'Buckley TK, Morrow AL. Cellular GABAergic Neuroactive Steroid (3α,5α)-3-Hydroxy-Pregnan-20-One (3α,5α-THP) Immunostaining Levels Are Increased in the Ventral Tegmental Area of Human Alcohol Use Disorder Patients: A Postmortem Study. Alcohol Clin Exp Res. 2017 Feb;41(2):299-311. doi: 10.1111/acer.13300. PubMed PMID: 28068457; PubMed Central PMCID: PMC5272786.

Hwa L, Besheer J, Kash T. Glutamate plasticity woven through the progression to alcohol use disorder: a multi-circuit perspective. F1000Res. 2017 Mar 21;6:298. doi: 10.12688/f1000research.9609.1. eCollection 2017. Review. PubMed PMID: 28413623; PubMed Central PMCID: PMC5365217.

Jimenez VA, Grant KA. Studies using macaque monkeys to address excessive alcohol drinking and stress interactions. Neuropharmacology. 2017 Mar 24. pii: S0028-3908(17)30120-X. doi: 10.1016/j.neuropharm.2017.03.027. [Epub ahead of print] Review. PubMed PMID: 28347838.

King CE, Griffin WC, Luderman LN, Kates MM, McGinty JF, Becker HC. Oxytocin Reduces Ethanol Self-Administration in Mice. Alcohol Clin Exp Res. 2017 Feb 17. doi: 10.1111/acer.13359. [Epub ahead of print] PubMed PMID: 28212464.

Lopez MF, Miles MF, Williams RW, Becker HC. Variable effects of chronic intermittent ethanol exposure on ethanol drinking in a genetically diverse mouse cohort. Alcohol. 2017 Feb;58:73-82. doi: 10.1016/j.alcohol.2016.09.003. PubMed PMID: 27793543.

McCaul ME, Hutton HE, Stephens MA, Xu X, Wand GS. Anxiety, Anxiety Sensitivity, and Perceived Stress as Predictors of Recent Drinking, Alcohol Craving, and Social Stress Response in Heavy Drinkers. Alcohol Clin Exp Res. 2017 Apr;41(4):836-845. doi: 10.1111/acer.13350. Epub 2017 Mar 9. PubMed PMID: 28281290; PubMed Central PMCID: PMC5388456.

Nimitvilai S, Lopez MF, Mulholland PJ, Woodward JJ. Ethanol Dependence Abolishes Monoamine and GIRK (Kir3) Channel Inhibition of Orbitofrontal Cortex Excitability. Neuropsychopharmacology. 2017 Jan 31. doi: 10.1038/npp.2017.22. [Epub ahead of print] PubMed PMID: 28139680.

Nimitvilai S, Uys JD, Woodward JJ, Randall PK, Ball LE, Williams RW, Jones BC, Lu L, Grant KA, Mulholland PJ. Orbitofrontal neuroadaptations and cross-species synaptic biomarkers in heavy drinking macaques. J Neurosci. 2017 Mar 7. pii: 0133-17. doi: 10.1523/JNEUROSCI.0133-17.2017. [Epub ahead of print] PubMed PMID: 28270566.

Niu LN, Jee SE, Jiao K, Tonggu L, Li M, Wang L, Yang YD, Bian JH, Breschi L, Jang SS, Chen JH, Pashley DH, Tay FR. Collagen intrafibrillar mineralization as a result of the balance between osmotic equilibrium and electroneutrality. Nat Mater. 2017 Mar;16(3):370-378. doi: 10.1038/nmat4789. PubMed PMID: 27820813; PubMed Central PMCID: PMC5321866.

Porcu P, O'Buckley TK, Lopez MF, Becker HC, Miles MF, Williams RW, Morrow AL. Initial genetic dissection of serum neuroactive steroids following chronic intermittent ethanol across BXD mouse strains. Alcohol. 2017 Feb;58:107-125. doi: 10.1016/j.alcohol.2016.07.011. PubMed PMID: 27884493.

Radke AK, Jury NJ, Kocharian A, Marcinkiewcz CA, Lowery-Gionta EG, Pleil KE, McElligott ZA, McKlveen JM, Kash TL, Holmes A. Chronic EtOH effects on putative measures of compulsive behavior in mice. Addict Biol. 2017 Mar;22(2):423-434. doi: 10.1111/adb.12342. Epub 2015 Dec 21. PubMed PMID: 26687341; PubMed Central PMCID: PMC4916036.

Rinker JA, Fulmer DB, Trantham-Davidson H, Smith ML, Williams RW, Lopez MF, Randall PK, Chandler LJ, Miles MF, Becker HC, Mulholland PJ. Differential potassium channel gene regulation in BXD mice reveals novel targets for pharmacogenetic therapies to reduce heavy alcohol drinking. Alcohol. 2017 Feb;58:33-45. doi: 10.1016/j.alcohol.2016.05.007. PubMed PMID: 27432260; PubMed Central PMCID: PMC5191998.

van der Vaart AD, Wolstenholme JT, Smith ML, Harris GM, Lopez MF, Wolen AR, Becker HC, Williams RW, Miles MF. The allostatic impact of chronic ethanol on gene expression: A genetic analysis of chronic intermittent ethanol treatment in the BXD cohort. Alcohol. 2017 Feb;58:93-106. doi: 10.1016/j.alcohol.2016.07.010. PubMed PMID: 27838001.

Weerts EM, Wand GS, Maher B, Xu X, Stephens MA, Yang X, McCaul ME. Independent and interactive effects of OPRM1 and DAT1 polymorphisms on alcohol consumption and subjective responses in social drinkers. Alcohol Clin Exp Res. 2017 Apr 4. doi: 10.1111/acer.13384. [Epub ahead of print] PubMed PMID: 28376280.

Wills TA, Baucum AJ 2nd, Holleran KM, Chen Y, Pasek JG, Delpire E, Tabb DL, Colbran RJ, Winder DG. Chronic intermittent alcohol disrupts the GluN2B-associated proteome and specifically regulates group I mGlu receptor-dependent long-term depression. Addict Biol. 2017 Mar;22(2):275-290. doi: 10.1111/adb.12319. Epub 2015 Nov 8. PubMed PMID: 26549202; PubMed Central PMCID: PMC4860359.